There seems to be an entire genre wrapped around the twist that the characters at the beginning of the story discovering that they are at a completely different scale than the characters at the end of the story.

This one is all about a group discovering that the liquid falling from the sky is urine.

The best part, though, is the sound effect in the top left of the page.

(Heavy Metal issue #165, November 1996 – Page 86 Pee Pee by Frezzato)